NEW HUMAN CLINICAL STUDY SUPPORTS ADIPONECTIN AND AMPK ACTIVATION

The fat oxidation ingredient is a plant-based compound that helps regulate glucose and lipid metabolism through the adiponectin and AMPK signaling pathway. 

 

The newest human clinical study, published in the Journal of Biochemistry and Biotechnology, examined the effects of the plant-based compound on hyperglycemia and dyslipidemia regulation and its mechanism of action in pre-diabetic with hyperlipidemia human participants. The randomized, double-blind, crossover clinical trial measured fasting blood glucose and lipids, oral glucose-tolerance-test, small dense low-density lipoprotein-cholesterol (sdLDL-C), high-density lipoprotein-cholesterol (HDL-C), adiponectin, HbA1C, and adenosine monophosphate-activated protease kinase (AMPK). 

 

After 6 weeks of the patented plant-based compound supplementation, fasting blood glucose and area under the curve (AUC) were significantly decreased by 10.1% and 12.69% (p<0.05), respectively. Triglycerides and sdLDL-C were significantly decreased by 31.06% and 19.96% (p<0.05), respectively, in the test group than in the placebo group. HDL-C, adiponectin, and AMPK were significantly increased by 11.78%, 22.07%, and 12.72% (p<0.05), respectively in the patented plant-based compound supplementation group than in the placebo group. The results demonstrate that oral supplementation with the plant-based compound reduces hyperglycemia and dyslipidemia without adverse events. 

 

Richard – the president, stated: “Outcomes of our two trials to date suggest the plant-based compound may support glucose and cholesterol health as well as weight management. Insulin resistance increases hunger and leads to more food intake. We’ve seen that the plant-based compound reduced insulin resistance and increased fatty acid breakdown and can be part of an effective weight management program when accompanied by lower caloric intake, increased physical activities, quality sleep, and absence of underlying hormonal imbalance, and chronic inflammation. We’re excited to see how this finding helps consumers with their metabolic health journey.” 

With these new insights, the future is bright for health and wellness brands. 

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